Alec Pokrandt

We have the tools today to do so much genetic engineering, more than we have the resources to actually perform. So when trying to prioritize, my reasoning led me to the idea of designing organisms to be easier to edit. To me that means things like installing in the germline a tool kit of editors, delivery systems, circuits for spatiotemporal control, and native systems for molecular characterization that are faster, cheaper, and require no tooling. If we can install a cell to cell transmission system in the germline, a developed eukaryote could be treated with a gRNA and/or DNA, and the cells themselves would do the rest of the work, replicating the payload and releasing it in vectors, resulting in exponential whole body editing in a developed organism.

Similarly, what if we designed an organism that is easier to treat? What systems could we install in the germline so that diseases are easier to treat?

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(it was not a good investment, lol, I lost 90% of the money I put in companies like Beam, Prime, Editas, CRISPR, Verve, Caribou)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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I've tried to sell various things online over the years, I've flipped houses, generators, cars... but the one thing I actually care about is genetic engineering. I applied to competitive PhD programs, Feng Zhang's lab for example, but got nowhere. So I'm now searching for path to be a genetic engineer.

 

I understand that adding team members has its risks, so I'd thrilled to even do an internship. Given the opportunity to prove myself, I will deliver.